When Predictive Mechanisms Go Wrong: Disordered Visual Synchrony Thresholds in Schizophrenia

When predictive mechanisms go wrong: disordered visual synchrony thresholds in schizophrenia.

Patients with schizophrenia display an impaired sense of temporal continuity, and we showed that they judge events as being simultaneous even in case of large onset asynchronies. We check here whether this means a fusion of events in time, or on the contrary, a segregation of events and a deficit in coding time-event structure. Subjects decided whether 2 squares were displayed simultaneously or...

When Things Go Wrong: Interrupting Conversations

This paper presents a true-concurrent approach to formalising integration of Small-to-Medium Enterprises (SMEs) with Web services. Our approach formalises common notions in service-oriented computing such as conversations (interactions between clients and web services), multi-party conversations (interactions between multiple web services) and coordination protocols, which are central in a tran...

Periodic paralyses: when channels go wrong.

In 1865, Claude Bernard wrote that ‘the constancy of the internal milieu is the essential condition to a free and independent life’ [1]. It would be hard to find a more illustrative paradigm for that statement than for the case of hyperkalaemic periodic paralysis (HyperPP) reported by Grgic et al. in this issue [2]. A 14-year-old male was admitted for a sudden ascending paralysis involving the ...

Getting it right when things go wrong.

Schizophrenia: When neurons go astray

Recent prospective studies indicate that schizophrenia manifests itself in behavioural abnormalities much earlier than was previously thought, supporting the view that schizophrenia is a developmental disorder.